A lot of the time I go about my daily life with bits and pieces of the F Plus playing in my head at random points. It's a curse.
I do have a few favorites, though:
NO, WHAT IF KNOW IM DRUG DEAL?
Stog's anguished "I don't want to hear these words" from the second Bad Dragon thing
Pretty much any time Isfahan does a Metal Gear voice.
"Frenuloctomy". "Frenulec-TOme!" "Frenulec to me!"
"It's absolutely perfect for the hummingbird in your life."
Acier attempting to read the increasingly weird onomatopoeias for sneezing in episode 2 is classic.
Bunnybread's (brief) Basil Marceaux impression. Even if it killed the text, it still cracks me up.
I also have a serious love for Kumquatxop/Kumquatxop Lite weird voices:
MYYYYYYYYYY NAAAAAAAME IS MICHAEL BARRIER. And my brain is so big that my head won't fit on your screen.
TODAY, MY FRIEND MESSAGED ME ON FACEBOOOOOOOOOOOOOOOOOOOK!!!!!!
TONIGHT'S MOON IS THE WANING GIBBOUS 87% FUUULLL. NOW HERE'S AL ROPER WITH THE WEATHER.