Episode 50: What's Louisville Got To Do With It?, because it tore me between laughing at all of the bizarre methods the featured person was taking to keep out the NWO gangstalker projected sound noises, and feeling sorry for this individual who was possibly going through a lot of pain, however much of it self-induced. The episode left an impact on how I think about the average internet weirdo, how the little slices of their lives they give us in between bizarre outbursts can tell us so much about their personal circumstances, and how those circumstances can possibly lead to the behaviors that make them stand out to us. It also taught me that people actually wear tinfoil hats - who knew!
The episodes about multiples, fat activists (good god that name), and the recent one about dumb parents giving dumb advice have also become my favorites almost solely because they had me laughing and alternatively being in-fucking-furiating.
I also really liked Boot's "...and then you fuckin' eat it." from the second recipe episode, because it just sums up so well the view that anyone who follows those recipes must have towards food. If you have no qualms with actually eating fucking marshmallow sugar slop then you must have had your taste-buds cauterized, and you just fuckin eat any food that's placed in front of you. That episode in general was spectacular not only because the humor was dead-on, but, as Lemon explains at the end of the podcast, the collection of recipes that were read illustrated the trend towards providing a step-by-step guide to finding the last three or four things in the pantry that might not induce vomiting when combined and dumping them in a pan (or trough).