I think we are focusing way too much on attacking Dozerfleet personally, trying to mock his personal failings and struggles in life. If we are trying to make this cartoon more accessible to a larger audience, and have more meat in its general comedy (which is what I think Zekka was getting at with his post). Also, I apologize for spiting out the references and meme shit, I was trying to find some foundation and style from which we can expand from, and I see that we are past that phase now.
From how our ideas have developed, it appears that we want to make a clear message about Dozerfleet's ideology and egotism, which alienates him from performing well as socially functioning human being, as well as a creator. I think we can express this pretty well in a single, five minute skit, but a lot of people's proposals for the plot appear to be a bit overly ambitious and reference heavy. I like Aljonso's idea, but I think that would work better for an entire television episode, not a five minute short. I think Zekka is spot on when he talks about expanding out from a single concept, but always linking back to that concept, even if you are making a reference.
What I personally think we should focus on is Dozerfleet's casual sexism, both because it is one of his most pervasive themes throughout his 'work,' and because it's a pretty pervasive thing throughout the internet in general.
While the audience for this short is primarily fans of the F Plus and people on Ballpit, we should at least try to make it accessible to a wider audience, I mean, I doubt Portaxx would wanna spend so much time animating something that is basically a five minute circle jerk. No, I think the character's and subject matter should be reference enough, at least for the major aspects of the short. We need to look at her previous short (the one with Pokemon being interviewed) for an example, because, while it is probably funnier to a well-versed fan of Pokemon, to someone like me, who has only passing knowledge of it, it was still very funny. Look at the F Plus's jokes as well, while they usually contain references to outside things, or even references to itself, it is always to take advantage of the absurdity of what they are referencing, and could be equally as funny if the original thing it stems from didn't exist.
Thus, my proposal for the plot is this (it takes a lot from Nikaer Drakin's suggestion):
The short is a PSA about STDs, which the Rhombus Tykes are here to explain to their impressionable young fans. At first the PSA is very childish in the way it explains things, trying to scoot around explaining what sex is by using almost baby language (this could be a nod to the adult babies stuff, but even if it isn't it relates back to the original idea). The audience surrogate, and ostensible main character is polly, the female of the group. She will be played as an incredibly naive character, while the others appear as figures of authority (though they are all ultimately mouths for Dozerfleet). The character of Polly at this point will represent the innocent and stupid side of the dichotomous image Dozerfleet has of women.
As the short goes on, however, the male shapes continually, and casually, present accusations against Polly, to her horror and constant attempt to defend herself. Each STD that they will explain through scenarios will have different characters playing out different roles, but it is always the rhombuses playing out these scenarios. In all of these scenarios, however, it is presented as if Polly (the stand in for all women) is responsible for everything bad that could possibly happen. Polly will challenge this, but because Dozerfleet is supposedly writing this, she will always be too stupid to break the flimsy arguments the others make.
Eventually, Polly will storm off because she does not want to deal with this abuse anymore, and one of the male shapes will have to take her place. Because Dozerfleet is now angry, the other shapes become much more aggressive to the character that has taken Polly's place (maybe Enclo) and start diverging from their original topic to the point where they are doing nothing but violently (comically) trying to assault the stand in for women. In the end, though, Polly returns to be the naive victim again, and Dozerfleet calms down, bringing the short back down to a more casual misogyny, like earlier.
You don't have to go with this exact idea, but I think the basic plot structure could work well with a comedy short based on repetition. If you object to anything said above, or just want to expand on what I have said, then I graciously await your response.