Well, I can think of at least one time when the F Plus actually mocked people I sort of agree with on a general level (John K and the rest of the animation purists, other than dumbass bigot Doug TenNaple obviously). It was still a really funny episode though.
I liked Rob the Parrot too, especially when he tells off the coke addict. You go, Rob!
Otherwise, hmm... does pity count? I felt a twinge of pity for the GAMERS HIP CLIP guy, just because he was so misguided. I would pity Joan Ocean, too, except she's probably making tons of money going on Bigfoot fart tours with dumbass tourists.
Oh, and if this counts, I am a huge fan of James Joyce. (As a writer! Of books!) I also own "Absurdistan", which was read in the Pinstriped Balls episode -- the lengthy excerpt with the Russian guy who's sleeping with the extremely hairy-bushed ethnic woman -- and it is a HILARIOUS book, intentionally so. Great satire. The back cover describes it as Catch-22 meets South Park, which kind of sums it up. Were I a rich woman, I would pay the Ridiculists to do a full audiobook version for my enjoyment.